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The initial discovery of senolytics involved bioinformatics and transcriptomics to evaluate RNA and protein expression profiles of senescent cells

The much larger, headline-grabbing numbers associated with cagrilintide in the press figures in the low-to-mid 20% range come from Phase 3 trials of CagriSema , the combination with semaglutide, and are company-reported topline results, not standalone-cagrilintide data and not the peer-reviewed Phase 2 result cited above

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